Medically known as ephelides, freckles are small, pigmented spots on the skin which typically occur in multiples. Freckles are usually inherited, though can occasionally be related to disorders such as xeroderma pigmentosum or neurofirbomatosis. Freckles occur when the pigment produced by skin cells (melanin) accumulates and become concentrated in small regions or spots. Since the production of this pigment is stimulated by ultraviolet (UV) radiation, exposure to UV sources – either solar or artificial – can increase the number freckles or darken the shade of their pigmentation. (more…)
What’s a freckle?
Monday, November 22nd, 2010The Fitzpatrick Scale
Wednesday, October 13th, 2010
The Fitzpatrick Scale (also known as skin type or phototype) is a system for classifying skin based on the amount of melanin naturally present in skin and its response to ultraviolet (UV) radiation exposure. It was developed in 1975, by Dr Thomas B. Fitzpatrick, a dermatologist at the Harvard Medical School. In the years since, the categories have been revised and refined and are still widely used today. (more…)
The evolution of human skin pigmentation: The delicate balance
Friday, July 16th, 2010
Skin colour is one of the most obvious and most variable traits humans possess. As visual creatures, people readily observe these differences in one another. Anthropologist, Dr. Nina Jablonski, and colleague George Chaplin have unraveled the mystery behind the diversity of this distinguishing characteristic in their article, ‘Human skin pigmentation as an adaptation to UV radiation’. The pair have presented the first complete theory of skin colour as an evolutionary adaptation.
Paeleotologists have long known that human ancestors once had bodies covered with dense hair. Several theories on the evolution of the present ‘hairless condition’ exist. In this case, the authors suggest this was in response to hot conditions and the need to lose body heat upon physical activity. As naked beings, their once-protected skin became exposed to a multitude of environmental elements, including abrasion, infection, various chemicals and weather conditions. At the same time as the disappearance of the majority of body hair, humans evolved skin that was a more resilient barrier to such hazards and also contained the protective pigment eumelanin (melanin).
Sex and sport impact sun protective behaviour and skin cancer risk
Thursday, June 10th, 2010
It is known that ultraviolet radiation is one of the most important risk factors contributing to non-melanoma and melanoma skin cancers. Athletes playing outdoor sports are exposed to a comparatively high amount of UV because of training and competition outdoors and thus athletes have an increased risk for cutaneous melanoma and other skin cancers.
A study has found that one in seven UK cricket players was urgently requested to see a specialist after discovering worrying moles during check-ups. For that reason the Professional Cricketer’s Association has organised screenings for all its members at dermatology specialists and already 15% of the male players were found to be in need of further investigation.
Sun and health: The Wall St Journal faces off
Wednesday, April 28th, 2010Earlier in the week, WSJ online published two articles exploring our relationship with the sun. This is something we’ve looked at extensively on the Clinuvel Blog (including the vitamin D debate), so we welcome discussion of it in the broader press. Squaring off are two senior WSJ journalists: Melinda Beck and Laura Landro.
Soybeans – a new sunscreen?
Thursday, March 25th, 2010
Scientists have announced a new method for creating a bio-based sunscreen active ingredient from refined soybean oil at the 239th National Meeting of the American Chemical Society (ACS).
The team, led by Dr Joseph Laszlo, has developed technology for converting soybean oil into an active ingredient for sunscreen products. It involves incorporating ferulic acid, found naturally in hundreds of plants, into soybean oil. The combination of ferulic acid and vegetable oil produces a water-resistant material capable of absorbing both UVA (320-400nm) and UVB (280-320nm) light. Both UVA and UVB play a role in causing skin cancer, while UVB is the direct cause of sunburn.
Study: Sunsmart message not heeded by many African Americans
Thursday, March 4th, 2010A US School of Public Health study published last week revealed that African Americans are largely ignoring sun safety messages, despite research showing that African Americans were more likely to die from melanoma, compared to fair skinned Americans.
The study, of 2187 African Americans living in California aged 18-95, revealed that only about 31% of those surveyed always engaged in sun-protective behavior, while 62.7% never wear sunscreen.
Sunscreen; proper application and considerations
Monday, February 8th, 2010
In our final post on sunscreen, we will discuss the proper advice and application of sunscreen to achieve optimal protection from UV radiation.
A recently published study found that, even with detailed guidance and individual instruction, trial participants still applied less than half the amount of sunscreen recommended. Participants who were instructed only by the product packaging used slightly more than a third of the required amount. This is an important gap in public knowledge, as SPF ratings are based on tests carried out with the recommended amounts of sunscreen.





